- 行业: Library & information science
- Number of terms: 152252
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The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
1) Hyperkalemia; higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs.
2) The presence of an abnormally high concentration of potassium in the blood -- called also hyperpotassemia.
Industry:Medical
1) A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
2) A chemical used in bleaches, dyes, cleansers, antiseptics, and disinfectants. In a concentrated form, it is toxic and irritating to tissues.
Industry:Medical
1) The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.
2) A neutral, highly reactive, toxic free radical commonly found in biological systems.
3) The chemical group or ion OH that consists of one atom of hydrogen and one of oxygen and is neutral or positively charged.
4) Hydroxide.
Industry:Medical
Muscular weakness or partial paralysis restricted to one side of the body (discharged with a residual partial right hemiparesis. )
Industry:Medical
1) Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc. ) is based on the relative amounts of arginine and lysine in each.
2) A histone is a protein that provides structural support to a chromosome. In order for very long DNA molecules to fit into the cell nucleus, they wrap around complexes of histone proteins, giving the chromosome a more compact shape. Some variants of histones are associated with the regulation of gene expression.
Industry:Medical
1) Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. The treatment may include administration of hormones or hormone analogs to the patient, or decreasing the level of hormones in the body by using hormone antagonists, or hormone ablation therapy. The concept covers but not limited to: intermittent or permanent hormone suppression or ablation in treatment of hormone-dependent tumors, hormone replacement therapy of any kind, hormonal component of gender reassignment therapy, hormonal contraception, surgical and radiation castration.
2) Treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body's natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone.
Industry:Medical
1) Anterior midline brain, cranial, and facial malformations resulting from the failure of the embryonic prosencephalon to undergo segmentation and cleavage. Alobar prosencephaly is the most severe form and features anophthalmia; cyclopia; severe mental retardation; cleft lip; cleft palate; seizures; and microcephaly. Semilobar holoprosencepaly is characterized by hypotelorism, microphthalmia, coloboma, nasal malformations, and variable degrees of mental retardation. Lobar holoprosencephaly is associated with mild (or absent) facial malformations and intellectual abilities that range from mild mental retardation to normal. Holoprosencephaly is associated with chromosome abnormalities.
2) Holoprosencephaly is a developmental disorder that results when the forebrain of the embryo fails to divide and form the right and left halves of the brain. The disorder produces a single-lobed brain structure and severe skull and facial abnormalities. Often the deformities cause babies to die before birth. In mild cases, babies are born with near-normal brain development and facial abnormalities involving cleft lip or cleft palate.
Industry:Medical
Molecular genetic testing to identify a set of closely linked segments of DNA; used in linkage analysis or when a given trait is in linkage disequilibrium with a marker or set of markers.
Industry:Medical
1) Likeness in structure between parts of different organisms due to evolutionary differentiation from the same or a corresponding part of a remote ancestor.
2) Similarity in DNA or protein sequences between individuals of the same species or among different species.
Industry:Medical
1) The presence of different alleles at one or more loci on homologous chromosomes.
2) Having the two genes at corresponding loci on homologous chromosomes different for one or more loci.
Industry:Medical