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DNA sequence variations that occur when a single nucleotide (A, T, C, or G) in the genome sequence is altered.
See also: mutation, polymorphism, single-gene disorder.
Industry:Biology
One method in which genetic traits are passed from parents to offspring. Named for Gregor Mendel, who first studied and recognised the existence of genes and this method of inheritance.
See also: autosomal dominant, recessive gene, sex-linked.
Industry:Biology
The study of human genetics by comparisons with model organisms such as mice, the fruit fly, and the bacterium E. coli..
Industry:Biology
Hereditary disorder caused by a mutant allele of a single gene (e.g., Duchenne muscular dystrophy, retinoblastoma, sickle cell disease).
See also: polygenic disorders.
Industry:Biology
A stage in mitosis or meiosis during which the chromosomes are aligned along the equatorial plane of the cell..
Industry:Biology
Nucleic acid base sequence that can form a double-stranded structure with another DNA fragment by following base-pairing rules (A pairs with T and C with G). The complementary sequence to GTAC for example, is CATG..
Industry:Biology
Any cell in the body except gametes and their precursors.
See also: gamete.
Industry:Biology
Sets of miniaturised chemical reaction areas that may also be used to test DNA fragments, antibodies, or proteins..
Industry:Biology
Trait that has a genetic component that does not follow strict Mendelian inheritance. May involve the interaction of two or more genes or gene-environment interactions.
See also: Mendelian inheritance, additive genetic effects.
Industry:Biology
Incorporating new genetic material into cells for therapeutic purposes. The new genetic material cannot be passed to offspring.
See also: gene therapy.
Industry:Biology
