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A technique used to identify genes, usually those that are associated with diseases, based on their location on a chromosome..
Industry:Biology
Individual primary recombinant clones (hosted in phage, cosmid, YAC, or other vector) that are placed in two-dimensional arrays in microtiter dishes. Each primary clone can be identified by the identity of the plate and the clone location (row and column) on that plate. Arrayed libraries of clones can be used for many applications, including screening for a specific gene or genomic region of interest.
See also: library, genomic library, gene chip technology.
Industry:Biology
A method of studying chromosomes in the interphase stage of the cell cycle..
Industry:Biology
The fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (i.e., a protein or RNA molecule).
See also: gene expression.
Industry:Biology
Putting sequenced fragments of DNA into their correct chromosomal positions..
Industry:Biology
Short preexisting polynucleotide chain to which new deoxyribonucleotides can be added by DNA polymerase..
Industry:Biology
Repeated copying of a piece of DNA; a characteristic of tumour cells.
See also: gene, oncogene.
Industry:Biology
A technique that uses X-ray film to visualise radioactively labelled molecules or fragments of molecules; used in analysing length and number of DNA fragments after they are separated by gel electrophoresis..
Industry:Biology
In genetics, the right of people to restrict access to their genetic information..
Industry:Biology
Development of cDNA microarrays from a large number of genes. Used to monitor and measure changes in gene expression for each gene represented on the chip..
Industry:Biology
