L'amico Fritz is an opera in three acts by Pietro Mascagni, premiered in 1891 from a libretto by P. Suardon (Nicola Daspuro) (with additions by Giovanni Targioni-Tozzetti), based on the French novel L'ami Fritz by Émile Erckmann and Pierre-Alexandre Chatrian.

While the opera enjoyed some success in its day and is probably Mascagni's most famous work after Cavalleria rusticana, today it is performed far more rarely than Cavalleria, which remains Mascagni's only enduringly popular work in America (though in Italy, L'amico Fritz and Iris are still in the active repertoire). The "Cherry Duet" between Fritz and Suzel in Act 2 is the best known piece in the opera and has never left the duet repertoire.

The opera was first performed in Rome at the Teatro Costanzi, on 31 October 1891. Other first performances include those in Hamburg on 16 January 1892 with Gustav Mahler conducting; in London on 23 May 1892 at the Royal Opera House, Covent Garden; and in Australia on 19 October 1893 at the Princess's Theatre in Melbourne.