Louise is an opera (roman musical) in four acts by Gustave Charpentier to an original French libretto by the composer, with some contributions by Saint-Pol-Roux, a symbolist poet and inspiration of the surrealists.

The opera depicts Parisian working-class life. However the city itself is in many ways the true star of this very atmospheric work - invoked at various points during the opera. A French example of verismo opera, it tells the story of the love between Louise, a seamstress living with her parents in Paris, and Julien, a young artist. It is the story of a young girl's desire for freedom (associated in her mind with her lover and the city of Paris).

Charpentier later wrote a sequel to Louise, the opera Julien, which describes the artistic aspirations of Louise’s suitor.

Louise premiered on 2 February 1900 at the Opéra-Comique conducted by André Messager in a production by Albert Carré. It was successful, reaching its 100th performance just over a year later; the 500th performance at the Opéra-Comique took place on 17 January 1921, and by the early 1950s it had reached over 950 performances. The opera helped launch the career of the soprano Mary Garden, who sang Louise in Act 3 at the eighth performance. On 30 April 1900 the Opéra-Comique director Albert Carré gave away 400 seats to Paris dressmakers.

The revival of Louise at the Opéra-Comique on 28 February 1950, with scenery after maquettes by Utrillo and Géori Boué in the title role, celebrated the 50th anniversary of its creation and the 90th birthday of its composer. Although it was hoped that Charpentier might conduct the performance, in the end André Cluytens did so, but with the composer conducting the 'Chant de l’apothéose' after the 3rd act.