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linearized multistage model

Sequence of steps in which (a) a multistage model is fitted to tumor incidence data; (b) the maximum linear term consistent with the data is calculated; (c) the low-dose slope of the dose-response function is equated to the coefficient of the maximum linear term; and (d) the resulting slope is then equated to the upper bound of potency.

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  • Walter Lane
  •  (Gold) 1356 分数
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