The study of basic interactions among the nervous, endocrine, and immune systems during development, homeostasis, and host defense responses to injury. In its clinical aspects, neuroimmunology focuses on diseases of the nervous system, such as myasthenia gravis and multiple sclerosis, which are caused by pathogenic autoimmune processes, and on nervous system manifestations of immunological diseases, such as primary and acquired immuno­deficiencies. Basic research in neuroimmunology is directed at defining the biochemical basis for the network of these interactions.