High throughput screening (HTS) is used in the identification of small molecules that may lead to new therapeutic or commercial developments. Utilizing robotics, miniaturization, computer-aided molecular design (CAMD), combinatorial organic synthesis (COS), and screening information managing systems (SIMS), it provides a rapid, cost-effective method to screen potential sources for novel molecules often used in drug development. Unlike conventional screening, high throughput screening deals with a wide variety of input samples. Each sample has its own set of data and tracking issues, and produces new experimental results.