Severe acute respiratory syndrome was first recognized in November 2002. An international outbreak involving 26 countries, 8098 cases, and 774 deaths subsequently developed, ending in July 2003. Since then, two isolated cases of SARS and one cluster of 11 cases including one death have been identified, resulting from the “escape” of SARS-associated coronavirus (CoV) from research laboratories. In addition, four isolated cases of SARS with no secondary cases were identified in December 2003 and January 2004. Aside from these scenarios, to date there has been no evidence of a large-scale reemergence of SARS. Regardless, much interest and research continues into better understanding SARS in order to be prepared for its possible reemergence and/or the emergence of other similar pathogens.